Multi-IO Expander

[XORadmin]

Hello. I am new to this community and the Nerdseq.

Is it acceptable to connect one source to the I2C Input A minijack on the front panel while simultaneously connecting another source to the I2C Input A pin connectors on the back?

Something like this:

ER-301 (follower) -> Nerdseq (i2c A - pin connectors)
Sweet Sixteen mkII -> Nerdseq (i2c A - minijack input)
Disting EX -> Nerdseq (i2c B pin connectors)

Thank you in advance.

That is possible but it wouldn't work like this. You could control only either the NerdSEQ or the ER301 with it but not both as both need to have a different address and the S16 doesn't support to control multiple addresses.

What would work would be (left side the leader, right side the follower):
S16 -> NerdSEQ A
NerdSEQ B-> DistingEX    
NerdSEQ B-> ER301

ER301 and disting set to different addresses. And you can use the S16 to control the NerdSEQ or ER301 + Disting then which is what you probably want to do I assume.