I2C Settings with F8R, CVM8, Just Friends?

[XORadmin]

Same issue occurs with CVM-8, which is in both leader/follower modes always. With only CVM-8 connected via I2C, I2C B Mode set to 'NS -> 16N 1-16', address Hex35 Dec53 (which matches what is set in CVM-8 configurator).

CVM-8 Leader...
Interestingly, CVM-8 works fine in leader mode with the following set:
I2C B Mode: 16N -> NS 1-16
I2C B Address: Hex: 31 Dec: 49

CVM-8 Follower...
But changing to the following in NerdSeq presents 'Message: I2C Error' in the CVM-8 configurator:
I2C B Mode: NS -> 16N 1-16
I2C B Address: Hex: 35 Dec: 53

Saving the project with the above for 'CVM-8 Follower', then restarting NerdSeq with Autoload Project set to 'On' immediately shows repeated 'I2C Error' in CVM-8 configurator.

So, whatever is causing 'I2C Error' to present in CVM-8 config I think is impacting both F8R and CVM-8, attempting to use them in follower mode.

Changing back to 'CVM-8 Leader' above, saving the project, then rebooting NerdSeq causes the I2C error to cease in CVM-8 configurator and the CVM-8 then works fine again (in leader mode).

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Also, I'm in a state now where only newly created NerdSeq projects will respond to I2C LRN, but existing projects with the same I2C Settings will not respond to I2C LRN?

A FR8 in leader mode need to be turned on after or with the NerdSEQ. If the NerdSEQ is not setup right when the FR8 tries to connect then a FR8 (which I still assume being a 16n clone) then it will not work anymore until the FR8 reboots.
As for the follower mode, 34 is the main base address that is used in a NS->16n configuration. But that is not an answer for a possible I2C error on the CVM8. 

What do the FR8 and CVM8 forums/manuals say about follower modes?